Gliclazide

Gliclazide) Diamicron or
Generic name: Glyklazayd
Brand name: Dyamykrvn (Diamicron)
Canadian names:
Apo-Gliclazide ®; Diamicron ® MR; Diamicron ®; Novo-Gliclazide; Rhoxal-gliclazide; Sandoz-Gliclazide
Dosage forms: tablets 80mg
Product types:
Tablets: 80 mg
Diamicron ®: pills 80 mg Canadian
Diamicron ® MR: 30 mg sustained-release tablets
Available in generic form: tablets 80 mg
Drug class: oral diabetes
Drug groups: oral anti-diabetic drug
Taking extra risk: high
Dependence: low
A version: Yes
The generic: No
Flower Klazyd a diabetes drug that stimulates insulin secretion from the pancreas, the sugar turns Paynn. For the treatment of adults with diabetes with a balanced diet that is low in sugar and fat intake, and appetite goes down. Regular exercise will constitute an important part of diabetes treatment.
The side effects are generally mild, but symptoms of poorly controlled diabetes will occur if the drug is not suitable.
Indications:
Diabetes mellitus type II
Side Effects
Dose Vvabsth mild gastrointestinal (including nausea, vomiting, diarrhea Yaybvst), Nvrksy,
Metallic taste in mouth, increased appetite, severe allergic reactions including cholestatic jaundice,
Leukopenia, Trvmbvsaytvpny, aplastic anemia syndrome, Stevens - Johnson, erythema multiforme, a form
Drug interactions:
Alcohol, allopurinol, Zdqarchhay triazole, steroidal and non-steroidal anti-inflammatory drugs,
Klramfnyl, monoamine oxidase inhibitors, beta blockers, adrenaline, inhibitors of ACE,
Thiazide diuretics, Klrprvmazyn, oral contraceptive pills, Dyazvksyd
Amount of time: 1 to 2 times daily (morning and evening meals).
Dosage for adults: 80 to 320 mg per day.
Onset of drug effect: within 1 hour.
Following effects: 12 to 24 hours.
Food recommendations: a low-fat, low-sugar diet, a person should be observed when taking the tablets appear to be effective. Get the recipe of the doctor.
Keep the medication in a sealed container in a cool, dry area away from children and light.
Forget a dose: Take as soon as remembered with food.
Stopping the drug: Do not stop taking this pill without a doctor because it may worsen symptoms.
Additional amounts: In all cases, the emergency room visit. Warning signs of low blood sugar, especially if much like fainting, sweating, chills, headaches and distractions that occur immediately liquids or eat sugary foods. Emergency Guide Refer to drug toxicity.
Adverse effects:
Rarely, serious side effects of this drug. Dizziness, confusion, chills, sweating and weakness could be symptoms of low blood sugar due to lack of food or have a very high amount Glyklazyd.
Symptoms - dizziness / drowsiness, frequent outbreaks, consult a physician in all cases.
Symptoms - fatigue / lack of energy, frequent outbreaks, consult a physician in all cases.
Symptoms - chills / chills, frequent outbreaks, cases, consult a doctor at all.
Symptoms - sweating / flushing, frequent outbreaks, cases, consult a doctor at all.
Symptoms - headache / nervousness, frequent outbreaks, cases, consult a doctor at all.
Symptoms - rash / itching Incidence rare cases, consult a doctor at all.
Symptoms - nausea / vomiting / regurgitation, incidence, rarely, in all cases, consult a doctor.
Symptoms - thirst, infrequent outbreaks, cases, consult a doctor at all.
Drug interactions:
Note: Some drugs have opposing effects Glyklazyd and thus raise blood sugar. These drugs include barbiturates, Kvtykvastrvyydha, oral contraceptives, estrogens, Diuretics, Ryfampsyn and nicotinic acid. Other drugs, such as warfarin, aspirin, anti-tuberculosis, the Klvfybryt, Mddhay beta inhibitors of ACE, inhibitors of monoamine oxidase (MAOIS), allopurinol, phenyl Bvtazvn, Svlfyn Pyrazvn, sulfonamides and Saymytydn increase the risk of hypoglycemia.
Caution:
Tell your doctor the following.
Recently suffered a severe infection or injury, long-term liver or kidney problems, thyroid problems, poor nutrition, the decision to become pregnant, Addison's disease, other drug use.
For pregnant women: Not recommended. The baby's blood sugar level may be lower than normal. Replacement of insulin during pregnancy because it can help control diabetes.
For women who are breastfeeding: This drug penetrates the breast milk and may lower blood sugar in infants.
For Infants and Children: not recommended.
For ages over 60 are more difficult to recognize the symptoms of low blood sugar. Reduce dosage if necessary.
Taking this drug while driving and hard work: If you feel sleepiness and dizziness, and confusion Do you do these things.
Alcohol: Avoid drinking alcohol. Because alcohol can disrupt diabetes control and Glyklazyd can bring the alcohol tolerance.
Long-term use:
It's nothing. Sugar in urine and blood tests are necessary from time to time. Regular assessment of the eyes, heart and kidneys are also recommended.
Contraindications:
Diabetes type I, patients with ketoacidosis, severe infections, stress, and trauma (in terms of oral medication to control blood sugar is not), severe renal impairment
Precautions in use:
Hepatic and renal impairment, elderly, malnourished patients, adrenal insufficiency and pituitary
Precautions:
- This is a short acting drug in patients at high risk incidence of hypoglycemia are appropriate.
- Hepatic drug metabolism, it is a good drug in renal failure. The blood glucose control is essential in the presence of renal impairment
Prescribed dose in adults:
Tablets: Initially, 80 to 160 mg, 160 mg twice daily in two equal parts; maximum dose of 320 mg. Drug should be taken with food.
Sustained-release tablets: 30 to 120 mg once daily.
Glyklazyd or other anti-diabetes medicines given amount of medication for diabetes exist., And the dosage should be adjusted for each person based on blood sugar.
The treatment of other sulfonylureas Klazyd mud altered, since the transmission is not necessary (unless the Klrprvpa Mead gradually transition time is within 1 to 2 weeks)
be. amounts of insulin the patient requires hospitalization or is used to change.
Elderly: the adult
Renal failure in severe renal failure is prohibited.
Liver failure in severe renal failure is prohibited.
Prescribed form should be taken with food. Anorexia or NPO drug if it is not consumed.
Adverse
Central nervous system: headache, agitation, confusion
Skin rash, redness, itching, hives. Sulfonylureas rarely a cause can be glare and porphyria cutanea tarda.
Endocrine and Metabolic: decreased sugar (depending on dose) and hyponatremia (low sodium levels)
Gastrointestinal: Nausea, vomiting, diarrhea, fullness of heart, gastritis
Blood: Granvlvsytvzys, leukopenia, thrombocytopenia, anemia,
Hepatic: jaundice, elevated liver enzymes and LDH
Miscellaneous: disulfiram reaction (very poor)
Contraindications: Hypersensitivity to flower Klazyd and sulfonylureas, and type 1 diabetes, diabetic ketoacidosis, pregnancy, lactation, liver and kidney failure
Concerns / special interest:
• Deaths Cardiac - Vascular: Compared with diet alone or diet with insulin, sulfonylurea drugs is associated with increased cardiovascular mortality. Although more research is needed in this area.
• impaired glucose: All sulfonylureas can cause severe Hyyvglysmy can occur when insufficient food intake, exercise has been severe and prolonged, and when alcohol or drugs are consumed sugar. Well Patients suffering from malnutrition, kidney and liver failure in the elderly should be used with caution.
• Allergy to sulfonamides: chemical similarities among sulfonamides, sulfonylureas, the Anhydraz carbonic inhibitors, thiazides and other diuretics arc (except Atakrynyk acid) exists., If allergic to sulfonamides of these products are prohibited because there is a risk of cross-reactivity .
Disease-related concerns:
• status-related stress: the stress (infection, fever, trauma, surgery) may need to be changed to insulin therapy.
Special cases:
• the safety and efficacy of these drugs in children has not been established.
Drug Interactions
Drugs inhibit ACE (captopril and enalapril) may be more effective Klazyd flower hypoglycemia.
Anabolic steroids: possible impact of further declines Klazyd sugar flower.
Beta blockers may decrease the effects of low blood sugar may Klazyd clay; signs of hidden sugar is decreased; Glykvzhnvlyz reduced in diabetics who suffer from low blood sugar can not be administered repeatedly.
Corticosteroids may be Hyprglaysmy. Regulating glucose is necessary drugs.
Cyclosporine: Cyclosporine increases serum Klazyd mud.
Fluoroquinolone (Syprvflvkzasyn) may increase the effect of sulfonylureas is hypoglycemia.
H2 blockers, antacids, and sodium bicarbonate: effect of hypoglycemia increases glucose is regulated.
Rifampin: increased metabolism and thus its effectiveness is low.
Lysylat years: The impact of reduced sugar increases Klazyd mud.
Sulfonamides: The impact of reduced sugar increases Klazyd mud.
Thiazide: The impact of reduced sugar flower Klazyd.
Warfarin: anticoagulant effect increases with sulfonylureas.
Miconazole: effect of hypoglycemia may be mud Klazyd more.
Barbiturates: effects of hypoglycemia may be mud Klazyd more.
Laboratory changes may lower serum sodium and urine osmolality and increased to 24 hours because mud Klazyd property has a mild diuresis.
Concentrations may be reduced by a factor of 8 and 11.
May increase the concentration of tissue plasminogen activator.
Interactions of ethanol and Plants
Ethanol from its use should be avoided. (Disulfiram reaction can cause hypoglycemia and rarely.)
Plant: The use of chromium, and gymnema garlic should be avoided. Can lead to hypoglycemia.
Pregnancy prohibited. Group C.
In pregnancy: a pair of passes. Sulfonylureas can cause hearing impairment. Defects have also been reported, but may be due to uncontrolled diabetes. Insulin is the drug of choice to control diabetes during pregnancy.
Lactation: excreted in breast milk is unknown. Due to hypoglycemia in infants breastfeeding is prohibited.
Nutrition Notes: Must be a meal. Symptoms is considered low blood sugar (pounding, palms sweating, dizziness).
Evaluation criteria: signs and symptoms of hypoglycemia, fasting glucose, hemoglobin A1C
Objective criteria: adults:
Fasting glucose less than 120 mg per deciliter
Hemoglobin A1C less than 7 percent
Patient Information: Patients should be an experienced person in the field of education, diabetes, symptoms of hypothyroidism, and Hyyvglysmy, exercise and nutrition, blood sugar control and other issues to discuss, eat regularly and avoid disordered eating, as well as their Quick Products Aljdb have sugar from too much sun exposure is avoided; bracelets warning can be medical.
Poisoning symptoms include excessive intake of severe hypoglycemia, seizures, brain damage, tingling of the lips and tongue, nausea, yawning, confusion, agitation, palpitations, sweating, unconsciousness and coma. Poisoning sulfonylureas may cause hypoglycemia, which well is treated with glucose (in mild to severe cases of oral and injectable).